What Can 55+ Labs Working Together Teach Us About the Brain in Meditation?

2024Biol. Psychiatry: Cognitive Neuroscience and NeuroimagingLoading citations…Download PDFView on Biol. Psychiatry: Cognitive Neuroscience and Neuroimagingdoi:10.1016/j.bpsc.2024.10.015

ENIGMA-Meditation: Worldwide Consortium for Neuroscientific Investigations of Meditation Practices

Ganesan, S., ..., Cain, J. A., ..., King, J.

In plain English

What's the Point?

Overview

This consortium paper launches ENIGMA-Meditation, a worldwide collaboration of 55+ sites pooling neuroimaging data to find reproducible neural mechanisms of meditation. Shared protocols aim to move meditation neuroscience from small, siloed studies to population-scale discovery.

Background

Meditation research has generated inconsistent findings, partly because studies are small and use very different methods. Large-scale collaboration has transformed other areas of psychiatry (e.g., ENIGMA)—can it do the same for contemplative science?

Methods

A consortium paper launching ENIGMA-Meditation: a worldwide collaboration across 55+ sites, with shared data elements and analytic pipelines designed to make results directly comparable across labs.

Findings

Defines the common infrastructure—study designs, imaging protocols, and data-sharing framework—needed to pool neuroimaging data across sites at scale.

Impact

Sets the stage for identifying reproducible neural mechanisms of meditation's therapeutic effects and moving the field from small, siloed studies to population-scale discovery.

Abstract

From the manuscript

ENIGMA-Meditation is a worldwide consortium spanning more than 55 sites that aggregates neuroimaging data to identify reproducible neural mechanisms of meditation. The paper defines shared common data elements, imaging protocols, and analytic pipelines to enable cross-site pooling and moves meditation neuroscience toward population-scale, reproducible discovery.

Related Topics
  • Meditation
  • Consortium
  • Neuroimaging

Visual summary

Infographic coming soon.

Infographic coming soon

Full citation

Ganesan, S., ..., Cain, J. A., ..., King, J. (2024). ENIGMA-Meditation: Worldwide Consortium for Neuroscientific Investigations of Meditation Practices. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

© 2026 Joshua Cain, PhDAll Rights ReservedLast Updated: July 2026